Michael Cordes

 

Biography:

Michael graduated with a B.S. in Chemistry from the University of Washington during which he interned both at Baylor with Dr. Solouki and at Washington with Dr. Matt Bush prior to joining the Gallagher Lab. He enjoys hiking, playing pickup soccer/basketball, and chess.

 

Current Area:

Michael works with tandem experimental Mass Spectrometry and Molecular Dynamics simulations for fundamental characterization of Electrospray Ionization and ion energetics in the gas phase.


 

Presentations:

Oral Presentations:

  1. "Comparing the Stability and Strength of Protein-Ligand Complexes in Positive- and Negative-Ion Mode Native-like Mass Spectrometry" Bannon, M.G.; Cordes, M.S.; Cupples, A.M.; Gallagher, E.S., 80th Southwest Regional Meeting of the American Chemical Society; Waco, Texas; October 20-23, 2024.

  2. “Modelling Protein Charging during Electrospray with Molecular Dynamics Protocol for Proton Exchange between Discrete Grotthuss Diffuse H3O+ and Proteins” Cordes, M.S.; Gallagher, E.S. 71st ASMS Conference on Mass Spectrometry and Allied Topics; Houston, Texas; June 4-8, 2023.

Poster Presentation:

  1. "Molecular Dynamics Simulations of Native-Protein Charging in Electrosprayed Droplets with Experimentally Relevant Composition" Cordes, M.S.; Bannon, M.G., Gallagher, E.S., 80th Southwest Regional Meeting of the American Chemical Society; Waco, Texas; October 20-23, 2024.

  2. “Towards Comprehensive Molecular Dynamics Simulations of Native-Protein Charging in Electrosprayed Droplets” Cordes, M.S.; Gallagher E.S., 72nd ASMS Conference on Mass Spectrometry and Allied Topics; Minneapolis, Minnesota; June 5-9, 2024.

  3. “Secondary Proton Transfer during Ion/Ion Reactions between Metal-Adducted Peptides and Fluoranthene” Gass, D.T.; Bannon, M.G.; Cordes, M.S.; Alberti, S.N.; Gallagher, E.S., 71st ASMS Conference on Mass Spectrometry and Allied Topics; Houston, Texas; June 4-8, 2023.

  4. “Determining the Gas-Phase Stability of Chloramphenicol Acetyltransferase (CAT) and the Effects of Ligand Binding” Edwards, A.N.; Blue, A.J.; Cordes, M.S.; Conforti, J.M.; Trakselis, M.A.; Gallagher, E.S., 71st ASMS Conference on Mass Spectrometry and Allied Topics; Houston, Texas; June 4-8, 2023.

  5. “Towards Understanding the Effect of Isoelectric Point on the Gas-Phase Stability of Proteins in Native MS” Edwards, A.N.; Cordes, M.S.; Gallagher, E.S., 71st ASMS Conference on Mass Spectrometry and Allied Topics; Houston, Texas; June 4-8, 2023.

  6. “Characterization of Carbohydrate Ionization Efficiencies in Electrospray as a Function of the Adducted Metal Ion” Cordes, M.S.; Gass, D.T.; Gallagher, E.S., 70th ASMS Conference on Mass Spectrometry and Allied Topics; Minneapolis, Minnesota; June 5-9, 2022.

  7. “Differences in the Stability of Metal-Carbohydrate Adducts Affect the Collisionally Dissociated Fragments Detected in Ion-Ion Reaction Spectra” Gass, D.T.; Cordes, M.S.; Alberti, S.; Gallagher, E.S. 70th ASMS Conference on Mass Spectrometry and Allied Topics; Minneapolis, Minnesota; June 5-9, 2022.

Publications:

  1. Cordes, M.S.; Gallagher, E.S. Molecular Dynamics Simulations of Native Protein Charging via Proton Transfer during Electrospray Ionization with Grotthuss Diffuse H3O+. Anal. Chem. 2024, 96 (10), 4146-4153. DOI: 10.1021/acs.analchem.3c05089

  2. Gass, D.T.; Cordes, M.S.; Alberti, S.N.; Kim, H.J.; Gallagher, E.S. Evidence of H/D Exchange within Metal-Adducted Carbohydrates after Ion/Ion-Dissociation Reactions. J. Am. Chem. Soc. 2023, 145 (44), 23972-23985. DOI: 10.1021/jacs.3c05793

  3. Edwards, A.N.; Blue, A.J., Conforti, J.M., Cordes, M.S.; Trakselis, M.A., Gallagher, E.S. Gas-phase stability and thermodynamics of ligand-bound, binary complexes of chloramphenicol acetyltransferase reveal negative cooperativity. Anal. Bioanal. Chem. 2023, 415 (25), 6201-6212. DOI: 10.1007/s00216-023-04891-5

 

Organizations:

American Society of Mass Spectrometry (ASMS)

 

Awards:

2022-2024 Baylor University Travel Award

Email: Michael_Cordes@baylor.edu

LinkedIn: linkedin.com/in/michael-cordes-132b0b176

Contact Information: